Advances in Pharmaceutical Development

DRA symposium

Pharmaceutical development, driven by the new challenges in health and society, is moving further with new and innovative technologies, characterization methods and manufacturing procedures for advancing drug formulation. This is a result of the joined forces between both academia and industry on investing time and resources on investigating, not only the fundamental scientific questions behind drug formulation and characterization, but also on applying the generated scientific knowledge in the development of better manufacturing procedures of the final drug product.

This symposium is aimed at those working in the field of pharmaceutical sciences, coming from both academia and industry, who want to hear from experts across their field. Focus will be given to the latest advances in drug formulation, characterization, manufacturing and computational methods.

Registration before 7 April

Programme 22 April 2025

Advances in the Formulation (Chair: Inês C. B. Martins)

09:00 Coffee and croissants
09:30 Introduction / welcome
Inês C. B. Martins and Thomas Rades, Department of Pharmacy, University of Copenhagen, Denmark
09:40

Advances in lipid-based drug delivery

Anette Müllertz, Department of Pharmacy, University of Copenhagen, Denmark

10:10

Order and disorder in pharmaceutical solids – Advances in solid-state drug delivery

Thomas Rades, Department of Pharmacy, University of Copenhagen, Denmark

10:40

Advances in nasal drug delivery
Regina Scherliess, Department of Pharmaceutics, Kiel University, Germany

11:10 

Coffee break, scientific discussions & poster session

11:40

Electrospun dressings for the treatment of psoriasis

Andrea Heinz, Department of Pharmacy, University of Copenhagen, Denmark

12:10

ASD and implant development made easy

Daniel Treffer, Meltprep GmbH, Graz, Austria

12:40

Lunch


Advances in the Characterization (Chair: Markus Lubda)

14:00

Introduction to Brillouin and low-frequency Raman spectroscopy for pharmaceutical applications

Karlis Berzins, Department of Pharmacy, University of Copenhagen, Denmark

14:30

Elucidating structural heterogeneities of pharmaceuticals with stimulated Raman scattering microscopy

Clare Strachan, Faculty of Pharmacy, University of Helsinki, Finland

15:00

From crystalline to amorphous solid forms: which tools can we use for their structural characterization?

Inês C. B. Martins, Department of Pharmacy, University of Copenhagen, Denmark

15:30

Coffee break, scientific discussions & poster session

16:00

Additive Manufacturing in Drug Formulation Characterization

Leonard Siebert, Department of Material Science, Faculty of Engineering, Kiel University, Germany

16:30

Characterisation in Early Product Development

Pirjo Tajarobi, Astra Zeneca, Gothenburg, Sweden

17:00

Lab tour, Merck & MeltPrep innovation showcase

18:30

Get together with finger food and drinks


Programme 23 April 2025

Advances in Pharmaceutical Manufacturing (Chair: Clare Strachan)

09:30 Coffee and croissants
10:00

Tailor‐Made doses of pharmaceuticals by tunable modular design

Natalja Genina, Department of Pharmacy, University of Copenhagen, Denmark

10:30

Technological challenges for the adoption of FDM 3D printing in pharmaceutical practice

Mateusz Kurek, Faculty of Pharmacy, Jagiellonian University Medical School, Poland

11:00

Make poorly soluble drugs great again

Korbinian Löbmann, Zerion, Copenhagen, Denmark

11:30

Coffee break, scientific discussions & poster session

12:00 

Enhancing Solubility of Small and Large Molecules with Polyvinyl Alcohol

Markus Lubda, Merck, Darmstadt, Germany

12:30

Latest advancements in additive manufacturing for solubility enhancement
Thomas Kipping, Merck, Darmstadt, Germany

13:00

Lunch


Advances in the Computational methods (Chair: Daniel Treffer)

14:30

New and advanced approaches for sample characterization by X-rays and electrons

Philip Hans, Department of Pharmacy, University of Copenhagen, Denmark

15:00

Experimental and digital formulation development for ionic liquid based cutaneous drug delivery systems

Stine Rønholt, Department of Pharmacy, University of Copenhagen, Denmark

Mark Jones, Molecular Quantum Solutions ApS, Copenhagen, Denmark

15:30

Effect of simulation box size and shear on the structure of amorphous hydrochlorothiazide

Michael Devlin, Center for Continuous Manufacturing and Crystallisation, University of Strathclyde, Glasgow, UK

16:00

Coffee break, scientific discussions & poster session

16:30

Artificial Intelligence based Co-crystal Prediction Tool

Mitali Bhagwat, Merck, Darmstadt, Germany

17:00

Computationally assisted design (CAD) for lipid and polymer based drug delivery systems

Alex Bunker, Faculty of Pharmacy, University of Helsinki, Finland

17:30

Solving crystal structures using a neural network

Anders Larsen, Department of Pharmacy, University of Copenhagen, Denmark

18:00

Conclusion and closing remarks


The symposium is organized on behalf of the graduate programme in pharmaceutical sciences, Drug Research Academy, by Associate Professor Inês C. B. Martins and Professor Thomas Rades, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen.

The symposium is free of charge and open for attendance by all interested parties. It is necessary to pre-register before 7 April.