Structural insights into the regulation of Ca2+/Calmodulin‐dependent protein kinase II (CaMKII)

DRA lecture held by Professor John Kuriyan, Department of Molecular and Cell Biology, Department of Chemistry, University of California, Berkeley, USA.

John Kuriyan’s lab studies the mechanism, evolution and structure of molecular switches, particularly kinases, that carry out cellular signal transduction. They use biochemical, biophysical, structural and cell biological techniques to elucidate the molecular mechanism of these important regulators and how they have changed during the course of evolution. Over the years, the Kuriyan lab has provided groundbreaking new biological insight into the structure-function of CaMKII, an oligomeric kinase that plays a central role in neuronal signaling and is essential for learning and memory. The lecture will provide insights into CaMKII and its complex regulation.

The lecture is organised on behalf of the graduate programme in pharmaceutical sciences, Drug Research Academy, by Associate Professor Petrine Wellendorph, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen.

The DRA lecture is free of charge and open for attendance by all interested parties. It is not necessary to pre-register.